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What is the primary purpose of neoadjuvant treatment?

  1. To eliminate cancer cells before surgery

  2. To shrink the tumor to increase the possibility of resectability

  3. To enhance recovery post-surgery

  4. To improve the patient's overall health

The correct answer is: To shrink the tumor to increase the possibility of resectability

The primary purpose of neoadjuvant treatment is to shrink the tumor to increase the possibility of resectability. Neoadjuvant therapy, which may include chemotherapy, radiation, or hormonal therapy, is administered before the main treatment, typically surgery. By reducing the size of the tumor, neoadjuvant treatment can make it easier to remove the cancerous tissue, improving surgical outcomes and allowing for more conservative surgical techniques. Additionally, this approach can also help assess the tumor's response to the treatment before surgery. A successful reduction in tumor size can lead to better surgical margins and a lower likelihood of cancer recurrence, ultimately improving prognosis. The focus here is not just on eliminating cancer cells (though this is a secondary effect) but directly on making the surgery more feasible and successful.